Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.0042 | 0.284 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 1 | 1 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.0042 | 0.284 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.2486 | 0.5 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.0042 | 0.284 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.0042 | 0.284 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.0042 | 0.284 | 0.5 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.0042 | 0.284 | 0.5 |
Echinococcus granulosus | lysosomal protective protein | 0.0042 | 0.284 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.2486 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 1 | 1 |
Brugia malayi | Serine carboxypeptidase F41C3.5 precursor | 0.0042 | 0.284 | 0.0472 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.2486 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.0042 | 0.284 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.2486 | 0.5 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.0042 | 0.284 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.2486 | 0.8751 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.0042 | 0.284 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 1 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.0042 | 0.284 | 0.5 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.0042 | 0.284 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.2486 | 0.8751 |
Echinococcus multilocularis | lysosomal protective protein | 0.0042 | 0.284 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.