Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | geminin | 0.0197 | 0.0927 | 0.0927 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.1419 | 0.8975 | 0.8975 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1575 | 1 | 0.5 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.1575 | 1 | 0.5 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.1419 | 0.8975 | 0.8975 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1575 | 1 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.1575 | 1 | 0.5 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.1575 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.0927 | 0.0927 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.1575 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.1575 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1575 | 1 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0056 | 0 | 0.5 |
Schistosoma mansoni | lysosomal protective protein precursor (cathepsin A) (carboxypeptidase | 0.0156 | 0.0655 | 0.0655 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0056 | 0 | 0.5 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.1575 | 1 | 0.5 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.1575 | 1 | 1 |
Echinococcus granulosus | lysosomal protective protein | 0.1575 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0056 | 0 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1575 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0056 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.0927 | 0.0927 |
Echinococcus multilocularis | geminin | 0.0197 | 0.0927 | 0.0927 |
Echinococcus multilocularis | lysosomal protective protein | 0.1575 | 1 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0056 | 0 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.1575 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.