Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.4694 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.1214 | 0 | 0.5 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.4694 | 1 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.1214 | 0 | 0.5 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.4694 | 1 | 0.5 |
Toxoplasma gondii | MAPEG family protein | 0.4694 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.