Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0413 | 0.0144 | 0.0153 |
Echinococcus granulosus | histone deacetylase 3 | 0.4784 | 0.8234 | 0.8234 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.4784 | 0.8234 | 0.8778 |
Giardia lamblia | Histone deacetylase | 0.4784 | 0.8234 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.2314 | 0.3662 | 0.3662 |
Trypanosoma brucei | histone deacetylase 3 | 0.5404 | 0.938 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.4784 | 0.8234 | 0.8778 |
Brugia malayi | Histone deacetylase family protein | 0.5404 | 0.938 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.5404 | 0.938 | 1 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.4784 | 0.8234 | 0.8778 |
Plasmodium falciparum | histone deacetylase, putative | 0.5404 | 0.938 | 1 |
Echinococcus multilocularis | histone deacetylase | 0.5404 | 0.938 | 0.938 |
Trypanosoma cruzi | histone deacetylase, putative | 0.5404 | 0.938 | 1 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0413 | 0.0144 | 0.0153 |
Echinococcus multilocularis | histone deacetylase 6 | 0.5404 | 0.938 | 0.938 |
Plasmodium vivax | histone deacetylase, putative | 0.2314 | 0.3662 | 0.3904 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4784 | 0.8234 | 1 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0413 | 0.0144 | 0.0153 |
Leishmania major | histone deacetylase, putative | 0.4784 | 0.8234 | 0.8778 |
Schistosoma mansoni | histone deacetylase | 0.4784 | 0.8234 | 0.8234 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.2314 | 0.3662 | 0.3662 |
Entamoeba histolytica | histone deacetylase, putative | 0.4784 | 0.8234 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.4784 | 0.8234 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.5404 | 0.938 | 0.938 |
Brugia malayi | Histone deacetylase family protein | 0.5404 | 0.938 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4784 | 0.8234 | 1 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.2314 | 0.3662 | 0.3904 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.5404 | 0.938 | 1 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.4784 | 0.8234 | 0.8778 |
Loa Loa (eye worm) | hypothetical protein | 0.4784 | 0.8234 | 0.8778 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.4784 | 0.8234 | 0.8778 |
Loa Loa (eye worm) | hypothetical protein | 0.309 | 0.5098 | 0.5435 |
Plasmodium vivax | histone deacetylase 2, putative | 0.5404 | 0.938 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.5404 | 0.938 | 0.938 |
Brugia malayi | Histone deacetylase 1 | 0.4784 | 0.8234 | 0.8778 |
Echinococcus granulosus | histone deacetylase 6 | 0.5404 | 0.938 | 0.938 |
Loa Loa (eye worm) | histone deacetylase | 0.5404 | 0.938 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.5739 | 1 | 1 |
Plasmodium vivax | histone deacetylase 1, putative | 0.4784 | 0.8234 | 0.8778 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.5404 | 0.938 | 1 |
Trypanosoma brucei | histone deacetylase, putative | 0.5404 | 0.938 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3425 | 0.5718 | 0.6096 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.2314 | 0.3662 | 0.3904 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0413 | 0.0144 | 0.0153 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.5404 | 0.938 | 0.938 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4784 | 0.8234 | 1 |
Schistosoma mansoni | histone deacetylase | 0.4784 | 0.8234 | 0.8234 |
Echinococcus multilocularis | histone deacetylase 1 | 0.4784 | 0.8234 | 0.8234 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.2314 | 0.3662 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2314 | 0.3662 | 0.3904 |
Trypanosoma cruzi | histone deacetylase, putative | 0.5404 | 0.938 | 1 |
Echinococcus granulosus | histone deacetylase | 0.5404 | 0.938 | 0.938 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.4784 | 0.8234 | 1 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.2314 | 0.3662 | 0.3904 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.4784 | 0.8234 | 0.8778 |
Brugia malayi | histone deacetylase 11 | 0.2314 | 0.3662 | 0.3904 |
Echinococcus granulosus | histone deacetylase 1 | 0.4784 | 0.8234 | 0.8234 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.4784 | 0.8234 | 0.8778 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.4784 | 0.8234 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.5739 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.4784 | 0.8234 | 0.8778 |
Trypanosoma cruzi | histone deacetylase, putative | 0.2314 | 0.3662 | 0.3904 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4784 | 0.8234 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4784 | 0.8234 | 1 |
Plasmodium falciparum | histone deacetylase 2 | 0.5404 | 0.938 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.5404 | 0.938 | 0.938 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0413 | 0.0144 | 0.0153 |
Trypanosoma brucei | histone deacetylase 4 | 0.5404 | 0.938 | 1 |
Echinococcus multilocularis | histone deacetylase 8 | 0.2314 | 0.3662 | 0.3662 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.4784 | 0.8234 | 0.8778 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.5404 | 0.938 | 0.938 |
Leishmania major | histone deacetylase, putative | 0.5404 | 0.938 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.2314 | 0.3662 | 0.3904 |
Leishmania major | histone deacetylase, putative | 0.5404 | 0.938 | 1 |
Echinococcus multilocularis | histone deacetylase 3 | 0.4784 | 0.8234 | 0.8234 |
Trypanosoma brucei | histone deacetylase 2 | 0.2314 | 0.3662 | 0.3904 |
Echinococcus granulosus | histone deacetylase 6 | 0.5404 | 0.938 | 0.938 |
Echinococcus granulosus | histone deacetylase 8 | 0.2314 | 0.3662 | 0.3662 |
Plasmodium falciparum | histone deacetylase 1 | 0.4784 | 0.8234 | 0.8778 |
Trichomonas vaginalis | histone deacetylase, putative | 0.4784 | 0.8234 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.4784 | 0.8234 | 0.8778 |
Plasmodium vivax | histone deacetylase, putative | 0.5404 | 0.938 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.