Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hexokinase type 2 | 0.0722 | 1 | 0.5 |
Plasmodium vivax | hexokinase, putative | 0.0722 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0722 | 1 | 0.5 |
Trypanosoma brucei | hexokinase, putative | 0.0722 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.0722 | 1 | 0.5 |
Echinococcus granulosus | hexokinase type 2 | 0.0722 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.0722 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0722 | 1 | 1 |
Onchocerca volvulus | 0.0722 | 1 | 1 | |
Schistosoma mansoni | hexokinase | 0.0722 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0722 | 1 | 1 |
Trypanosoma cruzi | hexokinase, putative | 0.0722 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.0722 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.0722 | 1 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.0722 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0722 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.0722 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.0722 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.0722 | 1 | 0.5 |
Onchocerca volvulus | 0.0722 | 1 | 1 | |
Loa Loa (eye worm) | hexokinase type II | 0.0722 | 1 | 1 |
Entamoeba histolytica | hexokinase 2 | 0.0722 | 1 | 0.5 |
Onchocerca volvulus | 0.0722 | 1 | 1 | |
Entamoeba histolytica | hexokinase 1 | 0.0722 | 1 | 0.5 |
Plasmodium falciparum | hexokinase | 0.0722 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0722 | 1 | 0.5 |
Toxoplasma gondii | hexokinase | 0.0722 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.0722 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.1468 | 0.1468 |
Loa Loa (eye worm) | hexokinase | 0.0722 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Relative activity (functional) | = 0 % | Evaluated for its relative defibrillating activity in male cats 10 min after injection at concentration 3 mg/Kg | ChEMBL. | 11677127 |
Relative activity (functional) | = 0 % | Evaluated for its relative defibrillating activity in male cats 10 min after injection at concentration 2 mg/Kg | ChEMBL. | 11677127 |
Relative activity (functional) | = 0 % | Evaluated for its relative defibrillating activity in male cats 10 min after injection at concentration 1 mg/Kg | ChEMBL. | 11677127 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.