Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.2744 | 1 | 1 | |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.2744 | 1 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.2744 | 1 | 1 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | LGC-31 protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Brugia malayi | Cation transporter family protein | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | GABA receptor subunit | 0.1478 | 0.1438 | 0.1438 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Onchocerca volvulus | 0.2744 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Brugia malayi | Cation transporter family protein | 0.2744 | 1 | 1 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.23 | 0.6995 | 0.6995 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.2744 | 1 | 1 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.1478 | 0.1438 | 0.1438 |
Schistosoma mansoni | nAChR subunit | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.2744 | 1 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.2744 | 1 | 1 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.2435 | 0.7911 | 0.7911 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Schistosoma mansoni | nAChR subunit | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Onchocerca volvulus | 0.1478 | 0.1438 | 0.1438 | |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.2744 | 1 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.2744 | 1 | 1 |
Brugia malayi | kinase, mitochondrial precursor | 0.2435 | 0.7911 | 0.7911 |
Echinococcus granulosus | nAChR subunit | 0.2744 | 1 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.2744 | 1 | 1 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.2744 | 1 | 1 |
Echinococcus multilocularis | nAChR subunit | 0.1478 | 0.1438 | 0.1438 |
Leishmania major | developmentally regulated phosphoprotein-like protein | 0.2435 | 0.7911 | 0.5 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Trypanosoma cruzi | developmentally regulated phosphoprotein, putative | 0.2435 | 0.7911 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.1478 | 0.1438 | 0.5 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.1478 | 0.1438 | 0.1438 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.2744 | 1 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.2744 | 1 | 1 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.1478 | 0.1438 | 0.1438 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.2435 | 0.7911 | 0.7911 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.2744 | 1 | 1 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.2744 | 1 | 1 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.2744 | 1 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.1478 | 0.1438 | 0.1438 |
Schistosoma mansoni | nAChR subunit | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.2744 | 1 | 1 |
Onchocerca volvulus | 0.2744 | 1 | 1 | |
Loa Loa (eye worm) | ACC-1 protein | 0.2744 | 1 | 1 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.1478 | 0.1438 | 0.1438 |
Brugia malayi | Cation transporter family protein | 0.2744 | 1 | 1 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.2744 | 1 | 1 |
Echinococcus multilocularis | nAChR subunit | 0.2744 | 1 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.2744 | 1 | 1 |
Trypanosoma brucei | developmentally regulated phosphoprotein | 0.2435 | 0.7911 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.2744 | 1 | 1 |
Onchocerca volvulus | 0.2744 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.2744 | 1 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.2744 | 1 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.2744 | 1 | 1 |
Onchocerca volvulus | 0.1478 | 0.1438 | 0.1438 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.1478 | 0.1438 | 0.1438 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.1478 | 0.1438 | 0.1438 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.2744 | 1 | 1 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.2435 | 0.7911 | 0.7911 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Schistosoma mansoni | nAChR subunit | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.2744 | 1 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Onchocerca volvulus | 0.2744 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1478 | 0.1438 | 0.1438 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.2744 | 1 | 1 |
Schistosoma mansoni | nAChR subunit | 0.2744 | 1 | 1 |
Echinococcus granulosus | nAChR subunit | 0.1478 | 0.1438 | 0.1438 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.2744 | 1 | 1 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.2744 | 1 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.2744 | 1 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.2744 | 1 | 1 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.2435 | 0.7911 | 0.7911 |
Loa Loa (eye worm) | hypothetical protein | 0.2435 | 0.7911 | 0.7911 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Schistosoma mansoni | nAChR subunit | 0.2744 | 1 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.2744 | 1 | 1 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.23 | 0.6995 | 0.6995 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2744 | 1 | 1 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.2744 | 1 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.2744 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.2744 | 1 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.2744 | 1 | 1 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.2744 | 1 | 1 |
Onchocerca volvulus | 0.2744 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.