Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0 | 0.5 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.2853 | 1 | 0.5 |
Toxoplasma gondii | MAPEG family protein | 0.2853 | 1 | 0.5 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.2853 | 1 | 0.5 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.2853 | 1 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ip (functional) | = 0.8 | Sensory evaluation was done for sweetness at a concentration of 631 p.p.m. against sample intensity relative to 10% sucrose. | ChEMBL. | 3965718 |
Pm (functional) | = 310 | Sensory evaluation was done for sweetness at a concentration of 631 p.p.m. against compound potency calculated on a molar basis . | ChEMBL. | 3965718 |
Pw (functional) | = 120 | Sensory evaluation was done for sweetness at a concentration of 631 p.p.m. against compound potency calculated on weight basis. | ChEMBL. | 3965718 |
Sensory evaluation (functional) | = 0 | Sensory evaluation was done at a concentration of 631 p.p.m. against property of bitterness. | ChEMBL. | 3965718 |
Sensory evaluation (functional) | = 4 | Sensory evaluation was done at a concentration of 631 p.p.m. against other properties. | ChEMBL. | 3965718 |
Sensory evaluation (functional) | = 96 | Sensory evaluation was done at a concentration of 631 p.p.m. against property of sweetness. | ChEMBL. | 3965718 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.