Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0097 | 0.0097 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0097 | 0.0097 |
Onchocerca volvulus | Peroxidasin homolog | 0.0032 | 0 | 0.5 |
Brugia malayi | Protein C21B10.09 in chromosome II | 0.6046 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0031 | 0.0031 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.6046 | 1 | 1 |
Onchocerca volvulus | 0.0032 | 0 | 0.5 | |
Onchocerca volvulus | Peroxidase homolog | 0.0032 | 0 | 0.5 |
Onchocerca volvulus | 0.0032 | 0 | 0.5 | |
Schistosoma mansoni | solute carrier family 33 (acetyl-CoA transporter | 0.6046 | 1 | 1 |
Echinococcus granulosus | solute carrier family 33 | 0.6046 | 1 | 1 |
Plasmodium falciparum | acetyl-CoA transporter, putative | 0.6046 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0005 | 0.0005 |
Echinococcus multilocularis | solute carrier family 33 | 0.6046 | 1 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0032 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0005 | 0.0005 |
Onchocerca volvulus | Peroxidase homolog | 0.0032 | 0 | 0.5 |
Toxoplasma gondii | Acetyl-coenzyme A transporter, putative | 0.6046 | 1 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0097 | 0.0097 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.0097 | 0.0097 |
Schistosoma mansoni | solute carrier family 33 (acetyl-CoA transporter | 0.6046 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0097 | 0.0097 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.0097 | 0.0097 |
Schistosoma mansoni | solute carrier family 33 (acetyl-CoA transporter | 0.2248 | 0.3684 | 0.3684 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0032 | 0 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0032 | 0 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0097 | 0.0097 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0005 | 0.0005 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0031 | 0.0031 |
Onchocerca volvulus | 0.0032 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.