Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.1822 | 0.8415 | 0.8332 |
Brugia malayi | Protein kinase domain containing protein | 0.1822 | 0.8415 | 0.8332 |
Schistosoma mansoni | tyrosine kinase | 0.0854 | 0.0495 | 0.0495 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.2016 | 1 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2016 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0854 | 0.0495 | 0.0495 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.1822 | 0.8415 | 0.8332 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.2016 | 1 | 0.5 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.2016 | 1 | 0.5 |
Echinococcus granulosus | insulin receptor | 0.1822 | 0.8415 | 0.8332 |
Echinococcus multilocularis | lysosomal protective protein | 0.2016 | 1 | 1 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.2016 | 1 | 1 |
Echinococcus granulosus | lysosomal protective protein | 0.2016 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2016 | 1 | 1 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.1816 | 0.837 | 0.8285 |
Schistosoma mansoni | tyrosine kinase | 0.1822 | 0.8415 | 0.8415 |
Schistosoma mansoni | tyrosine kinase | 0.0854 | 0.0495 | 0.0495 |
Schistosoma mansoni | tyrosine kinase | 0.1822 | 0.8415 | 0.8415 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2016 | 1 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.2016 | 1 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2016 | 1 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.2016 | 1 | 0.5 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.1816 | 0.837 | 0.8285 |
Loa Loa (eye worm) | hypothetical protein | 0.0968 | 0.1428 | 0.0981 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.1822 | 0.8415 | 0.8332 |
Echinococcus multilocularis | insulin receptor | 0.1822 | 0.8415 | 0.8332 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.2016 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.1028 | 0.1923 | 0.1503 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.2016 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.