Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | protein kinase, putative | 0.0253 | 0.0454 | 0.1809 |
Toxoplasma gondii | MAPEG family protein | 0.2147 | 1 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.063 | 0.2352 | 1 |
Echinococcus granulosus | aurora kinase A | 0.063 | 0.2352 | 0.2352 |
Echinococcus granulosus | serine/threonine protein kinase | 0.017 | 0.0035 | 0.0035 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.063 | 0.2352 | 1 |
Trypanosoma brucei | aurora B kinase | 0.063 | 0.2352 | 1 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.063 | 0.2352 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.063 | 0.2352 | 0.2325 |
Loa Loa (eye worm) | AUR protein kinase | 0.063 | 0.2352 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.063 | 0.2352 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0253 | 0.0454 | 0.1809 |
Loa Loa (eye worm) | AUR protein kinase | 0.063 | 0.2352 | 1 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.063 | 0.2352 | 1 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.017 | 0.0035 | 0.0035 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.017 | 0.0035 | 0.0035 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.063 | 0.2352 | 1 |
Entamoeba histolytica | protein kinase , putative | 0.063 | 0.2352 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.063 | 0.2352 | 1 |
Brugia malayi | serine/threonine protein kinase 6 | 0.063 | 0.2352 | 1 |
Toxoplasma gondii | aurora kinase | 0.063 | 0.2352 | 0.1988 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.2147 | 1 | 1 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.2147 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.063 | 0.2352 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.063 | 0.2352 | 1 |
Echinococcus multilocularis | aurora kinase A | 0.063 | 0.2352 | 0.2352 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.063 | 0.2352 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0253 | 0.0454 | 0.1809 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.017 | 0.0035 | 0.0035 |
Entamoeba histolytica | protein kinase, putative | 0.063 | 0.2352 | 1 |
Brugia malayi | serine/threonine kinase 12 | 0.063 | 0.2352 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.063 | 0.2352 | 1 |
Trypanosoma cruzi | aurora B kinase, putative | 0.063 | 0.2352 | 1 |
Leishmania major | protein kinase, putative | 0.063 | 0.2352 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.063 | 0.2352 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.063 | 0.2352 | 0.2352 |
Trichomonas vaginalis | AGC family protein kinase | 0.063 | 0.2352 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.017 | 0.0035 | 0.0035 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.063 | 0.2352 | 0.2352 |
Schistosoma mansoni | protein kinase | 0.063 | 0.2352 | 0.2325 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.2147 | 1 | 1 |
Giardia lamblia | Aurora kinase | 0.063 | 0.2352 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.