Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | transcription factor LCR-F1 | 0.0043 | 0.3091 | 0.3996 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.9669 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0043 | 0.3091 | 0.3091 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.3091 | 0.5 |
Echinococcus multilocularis | jun protein | 0.01 | 1 | 1 |
Echinococcus granulosus | jun protein | 0.01 | 1 | 1 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0088 | 0.8512 | 0.8512 |
Schistosoma mansoni | jun-related protein | 0.0081 | 0.7736 | 1 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0088 | 0.8512 | 0.8512 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0043 | 0.3091 | 0.3091 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.7736 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.01 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.3091 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.3091 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.3091 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.3091 | 0.3996 |
Onchocerca volvulus | 0.0078 | 0.7404 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0078 | 0.7404 | 0.6243 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.01 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
pKa | = 6.4 | pKa value of the compound was determined by using fluorescence emission spectra | ChEMBL. | 11677123 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.