Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0899 | 0.0899 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0899 | 0.0899 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.1665 | 0.2778 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1665 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1665 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0899 | 0.0899 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1665 | 0.5 |
Loa Loa (eye worm) | zinc finger protein | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0346 | 0.0346 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.5095 | 1 |
Echinococcus multilocularis | geminin | 0.0176 | 0.5095 | 0.4115 |
Echinococcus granulosus | zinc finger transcription factor gli2 | 0.0321 | 1 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | zinc finger transcription factor gli2 | 0.0321 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0074 | 0.1665 | 0.1665 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.1665 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.1665 | 0.2778 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0346 | 0.0346 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0899 | 0.0899 |
Echinococcus granulosus | geminin | 0.0176 | 0.5095 | 0.4115 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.5095 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.