Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0778 | 1 | 1 |
Schistosoma mansoni | tyrosinase precursor | 0.0778 | 1 | 1 |
Onchocerca volvulus | 0.0778 | 1 | 0.5 | |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0778 | 1 | 0.5 |
Onchocerca volvulus | 0.0778 | 1 | 0.5 | |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0141 | 0.142 | 0.5 |
Onchocerca volvulus | 0.0778 | 1 | 0.5 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0778 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0778 | 1 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 1 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0778 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 0.5 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0288 | 0.3407 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0288 | 0.3407 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0778 | 1 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0778 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 0.5 |
Onchocerca volvulus | 0.0778 | 1 | 0.5 | |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0778 | 1 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 0.5 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0141 | 0.142 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0778 | 1 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | tyrosinase precursor | 0.0778 | 1 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0141 | 0.142 | 0.5 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0778 | 1 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0288 | 0.3407 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.