Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | vivapain-2 | 0.0467 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.0467 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0873 | 0.2076 | 0.2076 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0467 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Echinococcus granulosus | cathepsin b | 0.2422 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0467 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0873 | 0.2076 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0467 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0873 | 0.2076 | 0.2076 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0873 | 0.2076 | 1 |
Toxoplasma gondii | cathepsin B | 0.0873 | 0.2076 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0467 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0873 | 0.2076 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2422 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2422 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2422 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0467 | 0 | 0.5 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Loa Loa (eye worm) | cathepsin B | 0.0873 | 0.2076 | 0.2076 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Plasmodium vivax | vivapain-2 | 0.0467 | 0 | 0.5 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0467 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.