Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | geminin | 0.0185 | 0.662 | 0.662 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0123 | 0.3769 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0184 | 0.6587 | 0.6587 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0123 | 0.3769 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0123 | 0.3769 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0259 | 1 | 1 |
Onchocerca volvulus | 0.0107 | 0.3018 | 0.5 | |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0184 | 0.6587 | 0.6587 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0259 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0184 | 0.6587 | 0.6587 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0123 | 0.3769 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.662 | 0.662 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0123 | 0.3769 | 1 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0123 | 0.3769 | 0.5 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0123 | 0.3769 | 0.3769 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0123 | 0.3769 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0259 | 1 | 0.5 |
Loa Loa (eye worm) | phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.662 | 0.662 |
Schistosoma mansoni | alpha-glucosidase | 0.0159 | 0.5408 | 0.5408 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0259 | 1 | 1 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0259 | 1 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0123 | 0.3769 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0123 | 0.3769 | 1 |
Echinococcus granulosus | geminin | 0.0185 | 0.662 | 0.662 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0259 | 1 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0259 | 1 | 1 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0259 | 1 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0159 | 0.5408 | 0.5408 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Brugia malayi | phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Brugia malayi | Isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0123 | 0.3769 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0259 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0184 | 0.6587 | 0.6587 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0123 | 0.3769 | 0.3769 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0123 | 0.3769 | 0.3769 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0184 | 0.6587 | 0.6587 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0259 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.