Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | geminin | 0.0178 | 0.4138 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0448 | 0.1083 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.4138 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0448 | 0.1083 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.198 | 0.198 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.1063 | 0.1063 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0448 | 0.0448 |
Onchocerca volvulus | TPPP family protein homolog | 0.0385 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.198 | 0.198 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0448 | 0.1083 |
Brugia malayi | hypothetical protein | 0.0318 | 0.8099 | 0.8099 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0448 | 0.1083 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0448 | 0.1083 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0448 | 0.1083 |
Loa Loa (eye worm) | p25-alpha family protein | 0.0385 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0178 | 0.4138 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.4138 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0318 | 0.8099 | 0.8099 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.198 | 0.198 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.1063 | 0.2569 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.198 | 0.198 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1063 | 0.1063 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0448 | 0.1083 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0448 | 0.0448 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.