Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.011 | 0 | 0.5 |
Echinococcus granulosus | prolyl endopeptidase | 0.0276 | 0.5247 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0276 | 0.5247 | 0.5 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0276 | 0.5247 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0276 | 0.5247 | 0.5 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0276 | 0.5247 | 0.5 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0276 | 0.5247 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.5247 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.011 | 0 | 0.5 |
Trypanosoma brucei | prolyl endopeptidase | 0.0276 | 0.5247 | 1 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0276 | 0.5247 | 0.5 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0247 | 0.4333 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.