Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2422 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2422 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0467 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0873 | 0.2076 | 0.2076 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Plasmodium vivax | vivapain-2 | 0.0467 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0467 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.2422 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0467 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0467 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0467 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0873 | 0.2076 | 0.2076 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Echinococcus multilocularis | cathepsin b | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0467 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.2422 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0873 | 0.2076 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0467 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0873 | 0.2076 | 0.2076 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0873 | 0.2076 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0467 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0873 | 0.2076 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0873 | 0.2076 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.