Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0467 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0873 | 0.2076 | 0.2076 |
Onchocerca volvulus | Cathepsin F homolog | 0.0467 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0467 | 0 | 0.5 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Echinococcus multilocularis | cathepsin b | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0467 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.2422 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0467 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0873 | 0.2076 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0873 | 0.2076 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0873 | 0.2076 | 0.2076 |
Onchocerca volvulus | Cathepsin L homolog | 0.0467 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0873 | 0.2076 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0873 | 0.2076 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2422 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2422 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2422 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0467 | 0 | 0.5 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0467 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Loa Loa (eye worm) | cathepsin B | 0.0873 | 0.2076 | 0.2076 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Plasmodium vivax | vivapain-2 | 0.0467 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.2422 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0873 | 0.2076 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0467 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2422 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2422 | 1 | 1 |
Onchocerca volvulus | 0.0467 | 0 | 0.5 | |
Onchocerca volvulus | 0.0467 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.