Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.0000010656 | 0.0000010656 |
Toxoplasma gondii | phospholipase D active site domain-containing protein | 0.0034 | 0.2141 | 1 |
Echinococcus multilocularis | phospholipase D | 0.0087 | 0.8592 | 0.8592 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0017 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0000010656 | 0.0000013208 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.0000010656 | 0.0000010656 |
Echinococcus granulosus | phospholipase D | 0.0087 | 0.8592 | 0.8592 |
Echinococcus granulosus | phospholipase D1 | 0.0098 | 1 | 1 |
Onchocerca volvulus | Putative phospholipase D | 0.0019 | 0.0208 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0017 | 0.0000010656 | 0.0000010656 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0017 | 0 | 0.5 |
Echinococcus multilocularis | phospholipase d3 | 0.0019 | 0.0208 | 0.0208 |
Brugia malayi | Phospholipase D. Active site motif family protein | 0.0034 | 0.2141 | 0.2141 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5791 | 0.7178 |
Schistosoma mansoni | transient receptor potential channel | 0.0017 | 0.0000010656 | 0.0000010656 |
Loa Loa (eye worm) | phospholipase D | 0.0019 | 0.0208 | 0.0258 |
Leishmania major | phosphatidylglycerophosphate synthase, putative | 0.0019 | 0.0208 | 1 |
Trypanosoma brucei | cardiolipin synthetase, putative | 0.0034 | 0.2141 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0000010656 | 0.0000013208 |
Echinococcus granulosus | phospholipase d3 | 0.0019 | 0.0208 | 0.0208 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.8068 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.0000010656 | 0.0000010656 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0000010656 | 0.0000013208 |
Trypanosoma cruzi | cardiolipin synthetase, putative | 0.0034 | 0.2141 | 1 |
Entamoeba histolytica | phospholipase D, putative | 0.0098 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0208 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5791 | 0.7178 |
Trypanosoma brucei | cardiolipin synthetase | 0.0034 | 0.2141 | 1 |
Schistosoma mansoni | phospholipase D | 0.0098 | 1 | 1 |
Brugia malayi | Phospholipase D. Active site motif family protein | 0.0019 | 0.0208 | 0.0208 |
Entamoeba histolytica | phospholipase D, putative | 0.0098 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.0000010656 | 0.0000010656 |
Brugia malayi | olfactory channel protein osm-9 | 0.0017 | 0.0000010656 | 0.0000010656 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.0000010656 | 0.0000010656 |
Echinococcus multilocularis | phospholipase D1 | 0.0098 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.8068 | 1 |
Trypanosoma cruzi | cardiolipin synthetase, putative | 0.0034 | 0.2141 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.0000010656 | 0.0000010656 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 22247790 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.