Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Squalene synthetase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.3937 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0 | 0.5 |
Trypanosoma cruzi | squalene synthase, putative | 0.0303 | 1 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.3937 | 1 |
Trypanosoma cruzi | squalene synthase, putative | 0.0303 | 1 | 0.5 |
Echinococcus multilocularis | geminin | 0.0177 | 0.3937 | 1 |
Echinococcus granulosus | geminin | 0.0177 | 0.3937 | 1 |
Trypanosoma brucei | squalene synthase, putative | 0.0303 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.