Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0942 | 0.2544 | 0.1999 |
Loa Loa (eye worm) | glutamate receptor | 0.1978 | 0.6977 | 0.6756 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1708 | 0.5823 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1708 | 0.5823 | 0.5518 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0823 | 0.2034 | 0.2034 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.1792 | 0.6181 | 0.5902 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.1233 | 0.3788 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2435 | 0.8933 | 0.8855 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1708 | 0.5823 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0766 | 0.179 | 0.1191 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1708 | 0.5823 | 0.5 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0964 | 0.2637 | 0.2637 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.1708 | 0.5823 | 0.4757 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.2249 | 0.8137 | 0.8137 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.1708 | 0.5823 | 0.4757 |
Loa Loa (eye worm) | hypothetical protein | 0.0942 | 0.2544 | 0.1999 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1708 | 0.5823 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.2684 | 1 | 1 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.2435 | 0.8933 | 0.8661 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.2435 | 0.8933 | 0.8661 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.2684 | 1 | 1 |
Loa Loa (eye worm) | glutamate receptor | 0.0778 | 0.1841 | 0.1245 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.2684 | 1 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.1708 | 0.5823 | 0.5823 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.1657 | 0.5603 | 0.448 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0964 | 0.2637 | 0.2099 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.2684 | 1 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.1657 | 0.5603 | 0.5603 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.2684 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1708 | 0.5823 | 0.5 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.1657 | 0.5603 | 0.448 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.1978 | 0.6977 | 0.6756 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.