Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | N-myristoyltransferase | 0.0114 | 1 | 1 |
Loa Loa (eye worm) | N-myristoyltransferase 2 | 0.0114 | 1 | 1 |
Trichomonas vaginalis | N-myristoyl transferase, putative | 0.0114 | 1 | 1 |
Entamoeba histolytica | glycylpeptide N-tetradecanoyltransferase, putative | 0.0114 | 1 | 1 |
Brugia malayi | CAAX amino terminal protease family protein | 0.0069 | 0.4136 | 0.4136 |
Trypanosoma cruzi | N-myristoyl transferase, putative | 0.0114 | 1 | 1 |
Trypanosoma brucei | N-myristoyltransferase | 0.0114 | 1 | 1 |
Plasmodium vivax | glycylpeptide N-tetradecanoyltransferase, putative | 0.0114 | 1 | 0.5 |
Trichomonas vaginalis | N-myristoyl transferase, putative | 0.0075 | 0.4878 | 0.1264 |
Echinococcus multilocularis | glycylpeptide N tetradecanoyltransferase | 0.0114 | 1 | 1 |
Trypanosoma cruzi | N-myristoyl transferase, putative | 0.0114 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.4136 | 0.4136 |
Giardia lamblia | CDC72 | 0.0114 | 1 | 1 |
Echinococcus granulosus | glycylpeptide N tetradecanoyltransferase | 0.0114 | 1 | 1 |
Trypanosoma brucei | N-myristoyl transferase, putative | 0.0114 | 1 | 1 |
Plasmodium falciparum | glycylpeptide N-tetradecanoyltransferase | 0.0114 | 1 | 0.5 |
Leishmania major | N-myristoyl transferase, putative | 0.0114 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.