Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0414 | 0.0531 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Schistosoma mansoni | amine GPCR | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Dopamine receptor protein 2 | 0.0414 | 0.0531 | 0.5 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0325 | 0.0345 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Dopamine receptor protein 1 | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0414 | 0.0531 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Brugia malayi | sulfakinin receptor protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Dopamine receptor | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | larval opioid receptor | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Schistosoma mansoni | amine GPCR | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | follicle stimulating hormone receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | G-protein coupled receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | adenoreceptor | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | G protein-coupled receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0414 | 0.0531 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0325 | 0.0345 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0414 | 0.0531 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0414 | 0.0531 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0414 | 0.0531 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | putative neuropeptide receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | RE15519p | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Mycobacterium leprae | Probable anthranilate phosphoribosyltransferase TrpD | 0.1403 | 0.2586 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Mycobacterium tuberculosis | Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) | 0.4969 | 1 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | myosin xvIII | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | AKH receptor | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | ORL1-like opioid receptor | 0.0414 | 0.0531 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | GnHR receptor homolog | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0414 | 0.0531 | 0.5 |
Mycobacterium ulcerans | thymidine phosphorylase | 0.4969 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Schistosoma mansoni | neuropeptide receptor | 0.0414 | 0.0531 | 0.5 |
Mycobacterium tuberculosis | Probable anthranilate phosphoribosyltransferase TrpD | 0.1403 | 0.2586 | 0.2586 |
Brugia malayi | G-protein coupled receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Schistosoma mansoni | biogenic amine receptor | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0325 | 0.0345 | 0.5 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0414 | 0.0531 | 0.5 |
Brugia malayi | Melatonin receptor type 1A | 0.0414 | 0.0531 | 0.5 |
Echinococcus multilocularis | thymidine phosphorylase | 0.4969 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Schistosoma mansoni | histamine h1 receptor | 0.0414 | 0.0531 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 0.0531 | 0.5 |
Mycobacterium ulcerans | anthranilate phosphoribosyltransferase | 0.1403 | 0.2586 | 0.2586 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0414 | 0.0531 | 0.5 |
Onchocerca volvulus | 0.0414 | 0.0531 | 0.5 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0414 | 0.0531 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.