Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | aminopeptidase, putative | 0.0122 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0372 | 0.3655 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.2497 | 0.683 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0122 | 0 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0122 | 0 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0122 | 0 | 0.5 |
Onchocerca volvulus | 0.0415 | 0.4284 | 1 | |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0122 | 0 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0415 | 0.4284 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0122 | 0 | 0.5 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0122 | 0 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0415 | 0.4284 | 1 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0122 | 0 | 0.5 |
Echinococcus multilocularis | aminopeptidase N | 0.0415 | 0.4284 | 0.4284 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0336 | 0.3125 | 0.8549 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0122 | 0 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0122 | 0 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0122 | 0 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0122 | 0 | 0.5 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0122 | 0 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0122 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.