Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | equilibrative nucleoside transporter | 0.0265 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0178 | 0.5993 | 0.5993 |
Echinococcus multilocularis | equilibrative nucleoside transporter protein | 0.0265 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0178 | 0.5993 | 0.5993 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.0265 | 1 | 0.5 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.0265 | 1 | 0.5 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.0265 | 1 | 0.5 |
Onchocerca volvulus | Equilibrative nucleoside transporter, putative homolog | 0.0265 | 1 | 0.5 |
Echinococcus granulosus | equilibrative nucleoside transporter 3 | 0.0265 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0265 | 1 | 0.5 |
Onchocerca volvulus | Equilibrative nucleoside transporter, putative homolog | 0.0265 | 1 | 0.5 |
Echinococcus multilocularis | equilibrative nucleoside transporter 3 | 0.0219 | 0.7879 | 0.7879 |
Entamoeba histolytica | nucleoside transporter, putative | 0.0265 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.5993 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0265 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.5993 | 1 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.0265 | 1 | 0.5 |
Echinococcus multilocularis | equilibrative nucleoside transporter 3 | 0.0265 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.