Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | sphingosine kinase A B | 0.0302 | 0.5 | 0.5 |
Schistosoma mansoni | sphingoid long chain base kinase | 0.0302 | 0.5 | 0.5 |
Echinococcus multilocularis | sphingosine kinase 1 | 0.0302 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0302 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0302 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0302 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 39.8107 uM | PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.