Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | ERCC1 nucleotide excision repair protein, putative | 0.0162 | 1 | 1 |
Trypanosoma brucei | DNA repair protein, putative | 0.007 | 0 | 0.5 |
Brugia malayi | ERCC4 domain containing protein | 0.0115 | 0.4902 | 1 |
Trypanosoma cruzi | DNA repair protein, putative | 0.007 | 0 | 0.5 |
Trichomonas vaginalis | excision repair cross-complementing 1 ercc1, putative | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | helix-hairpin-helix domain-containing protein family protein | 0.0162 | 1 | 1 |
Toxoplasma gondii | DNA repair protein rad10 subfamily protein | 0.0162 | 1 | 1 |
Echinococcus multilocularis | DNA excision repair protein ERCC 1 | 0.0162 | 1 | 1 |
Schistosoma mansoni | excision repair cross-complementing 1 ercc1 | 0.0162 | 1 | 1 |
Plasmodium vivax | ERCC1 nucleotide excision repair protein, putative | 0.0162 | 1 | 1 |
Entamoeba histolytica | DNA excision repair protein, putative | 0.0162 | 1 | 1 |
Trypanosoma cruzi | DNA repair protein, putative | 0.007 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.