Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | sodium:glucose cotransporter 2 | 2.4651 | 1 | 1 |
Schistosoma mansoni | inositol transporter | 2.4651 | 1 | 1 |
Echinococcus granulosus | solute carrier family 5 | 2.4651 | 1 | 1 |
Onchocerca volvulus | 0.629 | 0.1475 | 0.5 | |
Chlamydia trachomatis | DNA gyrase subunit A | 0.3114 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 5 | 2.4651 | 1 | 1 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.629 | 0.1475 | 1 |
Schistosoma mansoni | inositol transporter | 2.4651 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.629 | 0.1475 | 0.5 |
Mycobacterium tuberculosis | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.3114 | 0 | 0.5 |
Mycobacterium ulcerans | DNA gyrase subunit A | 0.3114 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.629 | 0.1475 | 0.5 |
Brugia malayi | GH02984p | 0.629 | 0.1475 | 0.5 |
Plasmodium falciparum | DNA gyrase subunit A | 0.3114 | 0 | 0.5 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 2.4651 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase subunit A | 0.3114 | 0 | 0.5 |
Brugia malayi | Sodium:solute symporter family protein | 0.629 | 0.1475 | 0.5 |
Treponema pallidum | DNA gyrase, subunit A (gyrA) | 0.3114 | 0 | 0.5 |
Plasmodium vivax | DNA gyrase subunit A, putative | 0.3114 | 0 | 0.5 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 2.4651 | 1 | 1 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 2.4651 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.