Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable D-amino acid oxidase Aao | 0.3757 | 0.9044 | 0.5 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1536 | 0.2829 | 0.5 |
Plasmodium falciparum | histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Brugia malayi | Histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Leishmania major | histone deacetylase, putative | 0.1536 | 0.2829 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0809 | 0.0794 | 0.2808 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0809 | 0.0794 | 0.0794 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1536 | 0.2829 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0809 | 0.0794 | 0.2808 |
Echinococcus multilocularis | histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Trypanosoma brucei | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.1536 | 0.2829 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0809 | 0.0794 | 0.2808 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.1536 | 0.2829 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0809 | 0.0794 | 0.0794 |
Schistosoma mansoni | histone deacetylase | 0.1536 | 0.2829 | 0.2829 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.1536 | 0.2829 | 0.2829 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1536 | 0.2829 | 0.5 |
Plasmodium vivax | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.1536 | 0.2829 | 0.2829 |
Echinococcus granulosus | histone deacetylase 6 | 0.0859 | 0.0933 | 0.3299 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0809 | 0.0794 | 0.0794 |
Brugia malayi | Histone deacetylase family protein | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Trypanosoma brucei | histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.0809 | 0.0794 | 0.2808 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Echinococcus granulosus | histone deacetylase 6 | 0.0809 | 0.0794 | 0.2808 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0809 | 0.0794 | 0.2808 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0859 | 0.0933 | 0.0933 |
Echinococcus multilocularis | histone deacetylase 3 | 0.1536 | 0.2829 | 1 |
Echinococcus granulosus | histone deacetylase 3 | 0.1536 | 0.2829 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1536 | 0.2829 | 0.2829 |
Loa Loa (eye worm) | histone deacetylase | 0.0809 | 0.0794 | 0.0794 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0809 | 0.0794 | 0.2808 |
Echinococcus granulosus | histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1536 | 0.2829 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0809 | 0.0794 | 0.2808 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0809 | 0.0794 | 0.2808 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.1536 | 0.2829 | 1 |
Trypanosoma brucei | histone deacetylase 4 | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Schistosoma mansoni | histone deacetylase | 0.1536 | 0.2829 | 0.2829 |
Echinococcus granulosus | histone deacetylase 7 | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Entamoeba histolytica | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.1536 | 0.2829 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1536 | 0.2829 | 1 |
Giardia lamblia | Histone deacetylase | 0.1536 | 0.2829 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Echinococcus multilocularis | histone deacetylase | 0.0809 | 0.0794 | 0.2808 |
Plasmodium vivax | histone deacetylase 1, putative | 0.1536 | 0.2829 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.1536 | 0.2829 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0859 | 0.0933 | 0.3299 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.