Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | monoglyceride lipase, putative | 0.0139 | 0.1746 | 1 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0139 | 0.1746 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0139 | 0.1746 | 0.5 |
Plasmodium vivax | PST-A protein | 0.0139 | 0.1746 | 1 |
Mycobacterium ulcerans | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD | 0.0433 | 0.8358 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0139 | 0.1746 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0139 | 0.1746 | 1 |
Mycobacterium ulcerans | lysophospholipase | 0.0139 | 0.1746 | 0.2089 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0139 | 0.1746 | 0.5 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0139 | 0.1746 | 1 |
Plasmodium falciparum | esterase, putative | 0.0139 | 0.1746 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0139 | 0.1746 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0139 | 0.1746 | 1 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0139 | 0.1746 | 0.5 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0139 | 0.1746 | 0.2129 |
Plasmodium falciparum | lysophospholipase, putative | 0.0139 | 0.1746 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0139 | 0.1746 | 0.2089 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0139 | 0.1746 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0139 | 0.1746 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0139 | 0.1746 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0139 | 0.1746 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0139 | 0.1746 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0139 | 0.1746 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0139 | 0.1746 | 1 |
Mycobacterium tuberculosis | 4,9-DHSA hydrolase | 0.0426 | 0.8202 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.