Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | bifunctional protein BirA | 0.2276 | 0.9183 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 28.59 umol/L | Inhibition of Electrophorus electricus AChE using acetylthiocholine as substrate after 10 mins by Ellman's method | ChEMBL. | 23462716 |
IC50 (binding) | = 62.69 umol/L | Inhibition of equine BChE using after 10 mins by Ellman's method | ChEMBL. | 23462716 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.