Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0183 | 0.5 | 0.5 | |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0183 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0183 | 0.5 | 0.5 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0183 | 0.5 | 0.5 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0183 | 0.5 | 0.5 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0183 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0183 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0183 | 0.5 | 0.5 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0183 | 0.5 | 0.5 |
Leishmania major | oxidoreductase-like protein | 0.0183 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.