Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.028 | 0.8875 | 0.8875 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.028 | 0.8875 | 0.8875 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.028 | 0.8875 | 0.8875 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.028 | 0.8875 | 0.8875 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0296 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.028 | 0.8875 | 0.8875 |
Giardia lamblia | Kinase, PLK | 0.0296 | 1 | 0.5 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0296 | 1 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.028 | 0.8875 | 0.8875 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.028 | 0.8875 | 0.8875 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.028 | 0.8875 | 0.8875 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.028 | 0.8875 | 0.8875 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.028 | 0.8875 | 0.8875 |
Trypanosoma brucei | polo-like protein kinase | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.028 | 0.8875 | 0.8875 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.028 | 0.8875 | 0.8875 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0296 | 1 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0296 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.028 | 0.8875 | 0.8875 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0296 | 1 | 0.5 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0296 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0296 | 1 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0296 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0296 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.