Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE D-AMINO ACID OXIDASE AAO | 0.4098 | 1 | 0.5 |
Echinococcus multilocularis | histone deacetylase | 0.0809 | 0.0794 | 0.2808 |
Echinococcus granulosus | histone deacetylase 3 | 0.1536 | 0.2829 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.0809 | 0.0794 | 0.2808 |
Plasmodium falciparum | histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Giardia lamblia | Histone deacetylase | 0.1536 | 0.2829 | 0.5 |
Mycobacterium tuberculosis | Probable D-amino acid oxidase Aao | 0.3757 | 0.9044 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.1536 | 0.2829 | 0.2829 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.1536 | 0.2829 | 1 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.1536 | 0.2829 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0809 | 0.0794 | 0.2808 |
Trypanosoma brucei | histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1536 | 0.2829 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Loa Loa (eye worm) | histone deacetylase | 0.0809 | 0.0794 | 0.0794 |
Leishmania major | histone deacetylase, putative | 0.1536 | 0.2829 | 1 |
Schistosoma mansoni | d-amino acid oxidase | 0.4098 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1536 | 0.2829 | 0.2829 |
Echinococcus granulosus | histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0525 | 0 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0809 | 0.0794 | 0.0794 |
Brugia malayi | Histone deacetylase family protein | 0.0809 | 0.0794 | 0.2808 |
Echinococcus granulosus | histone deacetylase | 0.0809 | 0.0794 | 0.2808 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.1536 | 0.2829 | 0.2829 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0859 | 0.0933 | 0.3299 |
Plasmodium vivax | histone deacetylase 1, putative | 0.1536 | 0.2829 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0809 | 0.0794 | 0.2808 |
Trypanosoma brucei | histone deacetylase 3 | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0809 | 0.0794 | 0.0794 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0809 | 0.0794 | 0.0794 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.1536 | 0.2829 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Echinococcus granulosus | histone deacetylase 6 | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1536 | 0.2829 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0809 | 0.0794 | 0.2808 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1536 | 0.2829 | 0.5 |
Schistosoma mansoni | histone deacetylase | 0.1536 | 0.2829 | 0.2829 |
Echinococcus multilocularis | histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Trypanosoma brucei | histone deacetylase 4 | 0.0809 | 0.0794 | 0.2808 |
Trypanosoma brucei | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Plasmodium vivax | histone deacetylase, putative | 0.0809 | 0.0794 | 0.2808 |
Entamoeba histolytica | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Brugia malayi | Histone deacetylase family protein | 0.0809 | 0.0794 | 0.2808 |
Leishmania major | histone deacetylase, putative | 0.1536 | 0.2829 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1536 | 0.2829 | 0.5 |
Echinococcus multilocularis | histone deacetylase 3 | 0.1536 | 0.2829 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0809 | 0.0794 | 0.2808 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1536 | 0.2829 | 0.5 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0859 | 0.0933 | 0.0933 |
Echinococcus granulosus | histone deacetylase 6 | 0.0859 | 0.0933 | 0.3299 |
Schistosoma mansoni | histone deacetylase | 0.1536 | 0.2829 | 0.2829 |
Mycobacterium ulcerans | D-amino acid oxidase Aao | 0.4098 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1536 | 0.2829 | 1 |
Brugia malayi | Histone deacetylase 1 | 0.1536 | 0.2829 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.1536 | 0.2829 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.