Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0528 | 0.5 | 0.5 |
Loa Loa (eye worm) | CDC7 protein kinase | 0.0528 | 0.5 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0528 | 0.5 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0528 | 0.5 | 0.5 |
Echinococcus granulosus | CDC7 cell division cycle 7 | 0.0528 | 0.5 | 0.5 |
Echinococcus multilocularis | CDC7 cell division cycle 7 | 0.0528 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0528 | 0.5 | 0.5 | |
Giardia lamblia | Kinase, CDC7 | 0.0528 | 0.5 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0528 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0528 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
pKB (functional) | = 7.68 | Inhibition of neurogenic contractions in guinea pig ileum mediated by histamine H3 receptors | ChEMBL. | 10560733 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.