Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 64 ug ml-1 | Antimicrobial activity against Escherichia coli DH52 after 24 hrs by microbroth dilution method | ChEMBL. | No reference |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity against Escherichia coli DH52 by two fold serial dilution method | ChEMBL. | 23312473 |
MIC80 (functional) | = 32 ug ml-1 | Antimicrobial activity against Candida albicans ATCC 90029 after 24 hrs by microbroth dilution method | ChEMBL. | No reference |
MIC80 (functional) | = 128 ug ml-1 | Antimicrobial activity against Saccharomyces cerevisiae ATCC 9763 after 24 hrs by microbroth dilution method | ChEMBL. | No reference |
MIC80 (functional) | = 256 ug ml-1 | Antimicrobial activity against Candida mycoderma after 24 hrs by microbroth dilution method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.