Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.1712 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0192 | 0.0192 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0749 | 0.4273 | 0.4273 |
Plasmodium vivax | histone deacetylase, putative | 0.1424 | 0.8287 | 0.8287 |
Echinococcus granulosus | histone deacetylase 7 | 0.1424 | 0.8287 | 0.8287 |
Loa Loa (eye worm) | hypothetical protein | 0.0705 | 0.4014 | 0.4014 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.1712 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 3 | 0.1712 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase | 0.1424 | 0.8287 | 0.8287 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.1712 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.1424 | 0.8287 | 0.8287 |
Echinococcus granulosus | histone deacetylase 6 | 0.1424 | 0.8287 | 0.8287 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.0749 | 0.4273 | 0.4273 |
Plasmodium falciparum | histone deacetylase, putative | 0.1424 | 0.8287 | 0.8287 |
Brugia malayi | Histone deacetylase family protein | 0.1424 | 0.8287 | 0.8287 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1712 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.1712 | 1 | 1 |
Brugia malayi | Histone deacetylase 1 | 0.1712 | 1 | 1 |
Entamoeba histolytica | histone deacetylase, putative | 0.1712 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1712 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0749 | 0.4273 | 0.4273 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1712 | 1 | 1 |
Leishmania major | histone deacetylase, putative | 0.1424 | 0.8287 | 0.8287 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1712 | 1 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0749 | 0.4273 | 0.4273 |
Schistosoma mansoni | histone deacetylase hda2 | 0.1454 | 0.8469 | 0.8469 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0072 | 0.0249 | 0.0249 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0749 | 0.4273 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.1424 | 0.8287 | 0.8287 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1424 | 0.8287 | 0.8287 |
Trypanosoma brucei | histone deacetylase 1 | 0.1712 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1712 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.1712 | 1 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.1424 | 0.8287 | 0.8287 |
Trypanosoma brucei | histone deacetylase 3 | 0.1424 | 0.8287 | 0.8287 |
Plasmodium vivax | histone deacetylase 1, putative | 0.1712 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1712 | 1 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0072 | 0.0249 | 0.0249 |
Echinococcus granulosus | histone deacetylase 3 | 0.1712 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1424 | 0.8287 | 0.8287 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0749 | 0.4273 | 0.4273 |
Echinococcus multilocularis | histone deacetylase 1 | 0.1712 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1424 | 0.8287 | 0.8287 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0079 | 0.0289 | 0.0289 |
Echinococcus granulosus | histone deacetylase 1 | 0.1712 | 1 | 1 |
Trypanosoma brucei | histone deacetylase, putative | 0.1424 | 0.8287 | 0.8287 |
Trypanosoma cruzi | histone deacetylase, putative | 0.1424 | 0.8287 | 0.8287 |
Leishmania major | histone deacetylase, putative | 0.1712 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0079 | 0.0289 | 0.0289 |
Leishmania major | histone deacetylase, putative | 0.1712 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.1712 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.1424 | 0.8287 | 0.8287 |
Echinococcus multilocularis | histone deacetylase 7 | 0.1424 | 0.8287 | 0.8287 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0749 | 0.4273 | 0.4273 |
Plasmodium falciparum | histone deacetylase 2 | 0.1424 | 0.8287 | 0.8287 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0068 | 0.0221 | 0.0221 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0749 | 0.4273 | 0.4273 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.1424 | 0.8287 | 0.8287 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1712 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1712 | 1 | 1 |
Brugia malayi | histone deacetylase 11 | 0.0749 | 0.4273 | 0.4273 |
Plasmodium vivax | histone deacetylase 2, putative | 0.1424 | 0.8287 | 0.8287 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.1712 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0749 | 0.4273 | 0.4273 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.1712 | 1 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.1424 | 0.8287 | 0.8287 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1424 | 0.8287 | 0.8287 |
Trypanosoma brucei | histone deacetylase 4 | 0.1424 | 0.8287 | 0.8287 |
Trypanosoma brucei | histone deacetylase 2 | 0.0749 | 0.4273 | 0.4273 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.1712 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0068 | 0.0221 | 0.0221 |
Trichomonas vaginalis | histone deacetylase, putative | 0.1712 | 1 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0072 | 0.0249 | 0.0249 |
Echinococcus multilocularis | histone deacetylase 6 | 0.1454 | 0.8469 | 0.8469 |
Echinococcus granulosus | histone deacetylase | 0.1424 | 0.8287 | 0.8287 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0749 | 0.4273 | 0.4273 |
Echinococcus granulosus | histone deacetylase 6 | 0.1454 | 0.8469 | 0.8469 |
Loa Loa (eye worm) | hypothetical protein | 0.0675 | 0.3832 | 0.3832 |
Giardia lamblia | Histone deacetylase | 0.1712 | 1 | 1 |
Plasmodium falciparum | histone deacetylase 1 | 0.1712 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 8 | 0.0749 | 0.4273 | 0.4273 |
Loa Loa (eye worm) | histone deacetylase | 0.1424 | 0.8287 | 0.8287 |
Leishmania major | histone deacetylase, putative | 0.1424 | 0.8287 | 0.8287 |
Plasmodium vivax | histone deacetylase, putative | 0.0749 | 0.4273 | 0.4273 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0072 | 0.0249 | 0.0249 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.1712 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.