Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0995 | 0.6522 | 1 |
Echinococcus multilocularis | hedgehog | 0.1302 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0995 | 0.6522 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0802 | 0.4338 | 0.6651 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0995 | 0.6522 | 0.6522 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0995 | 0.6522 | 0.6522 |
Onchocerca volvulus | Putative nachr subunit | 0.0995 | 0.6522 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0995 | 0.6522 | 1 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0995 | 0.6522 | 1 |
Onchocerca volvulus | 0.0995 | 0.6522 | 1 | |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0995 | 0.6522 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0995 | 0.6522 | 1 |
Onchocerca volvulus | 0.0995 | 0.6522 | 1 | |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0995 | 0.6522 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0995 | 0.6522 | 0.6522 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0995 | 0.6522 | 0.6522 |
Onchocerca volvulus | 0.0995 | 0.6522 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0949 | 0.5998 | 0.9196 |
Brugia malayi | Cation transporter family protein | 0.0995 | 0.6522 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0995 | 0.6522 | 0.6522 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0995 | 0.6522 | 0.6522 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.