Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cyclin B3 1 | 0.0598 | 0.1199 | 0.2347 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0936 | 0.2001 | 0.3764 |
Loa Loa (eye worm) | hypothetical protein | 0.2248 | 0.5109 | 0.5109 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 0.0372 | 0.0372 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Leishmania major | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.1265 | 0.2781 | 0.5444 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0936 | 0.2001 | 0.3917 |
Plasmodium falciparum | histone deacetylase 2 | 0.0641 | 0.1303 | 0.2363 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0936 | 0.2001 | 0.2001 |
Trichomonas vaginalis | cyclin D, putative | 0.0598 | 0.1199 | 0.2155 |
Entamoeba histolytica | cyclin, putative | 0.0598 | 0.1199 | 0.2155 |
Echinococcus granulosus | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0641 | 0.1303 | 0.2363 |
Brugia malayi | Cyclin C | 0.0144 | 0.0125 | 0.0106 |
Plasmodium vivax | histone deacetylase 1, putative | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0641 | 0.1303 | 0.2363 |
Echinococcus granulosus | histone deacetylase 8 | 0.0641 | 0.1303 | 0.255 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.2248 | 0.5109 | 0.5109 |
Giardia lamblia | Histone deacetylase | 0.2248 | 0.5109 | 1 |
Schistosoma mansoni | cyclins | 0.0598 | 0.1199 | 0.2347 |
Trichomonas vaginalis | cyclins, putative | 0.0846 | 0.1788 | 0.3337 |
Giardia lamblia | Kinase, CMGC CDK | 0.0936 | 0.2001 | 0.3764 |
Trichomonas vaginalis | cyclins, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0936 | 0.2001 | 0.3764 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0144 | 0.0125 | 0.0245 |
Trichomonas vaginalis | cyclin D, putative | 0.0598 | 0.1199 | 0.2155 |
Plasmodium vivax | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0936 | 0.2001 | 0.3764 |
Echinococcus granulosus | Cyclin L1 | 0.0144 | 0.0125 | 0.0245 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0641 | 0.1303 | 0.7081 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0641 | 0.1303 | 0.255 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0936 | 0.2001 | 0.3764 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.0144 | 0.0125 | 0.0245 |
Plasmodium vivax | protein kinase Crk2 | 0.0936 | 0.2001 | 0.3764 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0641 | 0.1303 | 0.255 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0125 | 0.0245 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.2248 | 0.5109 | 0.51 |
Schistosoma mansoni | cyclin k | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0936 | 0.2001 | 0.2001 |
Loa Loa (eye worm) | histone deacetylase | 0.0641 | 0.1303 | 0.1303 |
Trichomonas vaginalis | cyclin B, putative | 0.0846 | 0.1788 | 0.3337 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.2248 | 0.5109 | 0.5109 |
Schistosoma mansoni | Cyclin fold protein | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | histone deacetylase 3 | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0846 | 0.1788 | 0.3337 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.0144 | 0.0125 | 0.0125 |
Echinococcus multilocularis | Cyclin L1 | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | cyclin B | 0.0846 | 0.1788 | 0.35 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Entamoeba histolytica | cyclin family protein | 0.0598 | 0.1199 | 0.2155 |
Echinococcus granulosus | cyclins | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | cyclin y | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | CYL-1 protein | 0.0144 | 0.0125 | 0.0125 |
Echinococcus granulosus | cyclin B | 0.0846 | 0.1788 | 0.35 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.2248 | 0.5109 | 0.51 |
Echinococcus granulosus | cyclin dependent kinase | 0.0936 | 0.2001 | 0.3917 |
Trichomonas vaginalis | cyclin B3, putative | 0.0598 | 0.1199 | 0.2155 |
Echinococcus multilocularis | cyclin y | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trichomonas vaginalis | cyclin B, putative | 0.0598 | 0.1199 | 0.2155 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0641 | 0.1303 | 0.255 |
Brugia malayi | Histone deacetylase 1 | 0.2248 | 0.5109 | 0.51 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0641 | 0.1303 | 0.255 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0641 | 0.1303 | 0.255 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Echinococcus granulosus | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Echinococcus multilocularis | cyclin B | 0.0846 | 0.1788 | 0.35 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0846 | 0.1788 | 0.1788 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0641 | 0.1303 | 0.1303 |
Leishmania major | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Echinococcus multilocularis | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Brugia malayi | cell division control protein 2 homolog | 0.0936 | 0.2001 | 0.1986 |
Echinococcus multilocularis | cyclin t1 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | histone deacetylase 7 | 0.0641 | 0.1303 | 0.255 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0936 | 0.2001 | 0.3764 |
Plasmodium falciparum | cyclin | 0.0598 | 0.1199 | 0.2155 |
Echinococcus multilocularis | histone deacetylase 1 | 0.2248 | 0.5109 | 1 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.2248 | 0.5109 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | cyclin C | 0.0144 | 0.0125 | 0.0125 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Leishmania major | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0641 | 0.1303 | 0.1303 |
Onchocerca volvulus | 0.0846 | 0.1788 | 1 | |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Entamoeba histolytica | cyclin family protein | 0.0598 | 0.1199 | 0.2155 |
Brugia malayi | Histone deacetylase family protein | 0.0641 | 0.1303 | 0.1286 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0936 | 0.2001 | 0.3917 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0936 | 0.2001 | 0.2001 |
Giardia lamblia | Kinase, CMGC CDK | 0.0936 | 0.2001 | 0.3764 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0846 | 0.1788 | 0.1772 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0936 | 0.2001 | 0.3917 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Entamoeba histolytica | cyclin, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | cyclins, putative | 0.0846 | 0.1788 | 0.3337 |
Plasmodium falciparum | protein kinase 5 | 0.0936 | 0.2001 | 0.3764 |
Schistosoma mansoni | cyclin l | 0.0144 | 0.0125 | 0.0245 |
Plasmodium vivax | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | cyclin B3 | 0.1265 | 0.2781 | 0.5444 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.1265 | 0.2781 | 0.2767 |
Echinococcus granulosus | cyclin b3 | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Entamoeba histolytica | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Trichomonas vaginalis | cyclin A, putative | 0.0846 | 0.1788 | 0.3337 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.4312 | 1 | 1 |
Schistosoma mansoni | cyclin G | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Trichomonas vaginalis | cyclin B, putative | 0.0846 | 0.1788 | 0.3337 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Brugia malayi | hypothetical protein | 0.0144 | 0.0125 | 0.0106 |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.0144 | 0.0125 | 0.0245 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2248 | 0.5109 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.2248 | 0.5109 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | cyclin | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Toxoplasma gondii | hypothetical protein | 0.0453 | 0.0858 | 0.147 |
Loa Loa (eye worm) | hypothetical protein | 0.0641 | 0.1303 | 0.1303 |
Trypanosoma brucei | histone deacetylase 3 | 0.0641 | 0.1303 | 0.2363 |
Echinococcus multilocularis | cyclin y | 0.0144 | 0.0125 | 0.0245 |
Leishmania major | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0936 | 0.2001 | 0.3917 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Trypanosoma cruzi | cyclin 6, putative | 0.0846 | 0.1788 | 0.3337 |
Echinococcus granulosus | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.1265 | 0.2781 | 0.2781 |
Giardia lamblia | Cyclin A | 0.0598 | 0.1199 | 0.2155 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2248 | 0.5109 | 1 |
Plasmodium falciparum | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0641 | 0.1303 | 0.255 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | histone deacetylase | 0.0641 | 0.1303 | 0.255 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0846 | 0.1788 | 0.3337 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Brugia malayi | Histone deacetylase family protein | 0.0641 | 0.1303 | 0.1286 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0936 | 0.2001 | 0.3917 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0846 | 0.1788 | 0.3337 |
Trypanosoma brucei | histone deacetylase 4 | 0.0641 | 0.1303 | 0.2363 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0936 | 0.2001 | 0.3917 |
Echinococcus multilocularis | cyclin A3 4 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | histone deacetylase 1 | 0.2248 | 0.5109 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0598 | 0.1199 | 0.2155 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.1265 | 0.2781 | 0.5444 |
Echinococcus granulosus | cyclin A3 4 | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0641 | 0.1303 | 0.255 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0936 | 0.2001 | 0.3764 |
Trichomonas vaginalis | cyclin B, putative | 0.0846 | 0.1788 | 0.3337 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0846 | 0.1788 | 0.1788 |
Trichomonas vaginalis | cyclins, putative | 0.0846 | 0.1788 | 0.3337 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.2248 | 0.5109 | 1 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.0641 | 0.1303 | 0.2363 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0125 | 0.0125 |
Trypanosoma brucei | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Echinococcus granulosus | cyclin y | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | histone deacetylase | 0.2248 | 0.5109 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0936 | 0.2001 | 0.3764 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Plasmodium falciparum | histone deacetylase 1 | 0.2248 | 0.5109 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0936 | 0.2001 | 0.1986 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0944 | 0.2021 | 0.3803 |
Schistosoma mansoni | cyclin d | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0936 | 0.2001 | 0.3917 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0846 | 0.1788 | 0.1772 |
Echinococcus granulosus | cyclin t1 | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0641 | 0.1303 | 0.255 |
Trichomonas vaginalis | cyclin B, putative | 0.0846 | 0.1788 | 0.3337 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0641 | 0.1303 | 0.2363 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0936 | 0.2001 | 0.3764 |
Schistosoma mansoni | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0925 | 0.1975 | 0.1975 |
Trypanosoma cruzi | cyclin, putative | 0.0846 | 0.1788 | 0.3337 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0936 | 0.2001 | 0.3764 |
Leishmania major | cyclin | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | cyclins, putative | 0.0598 | 0.1199 | 0.2155 |
Giardia lamblia | Hypothetical protein | 0.0598 | 0.1199 | 0.2155 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | cyclin b3 | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | cyclin B3 1 | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | cyclin | 0.0144 | 0.0125 | 0.0245 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0846 | 0.1788 | 0.3337 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Brugia malayi | hypothetical protein | 0.0144 | 0.0125 | 0.0106 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0936 | 0.2001 | 0.3764 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.2248 | 0.5109 | 1 |
Echinococcus granulosus | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Brugia malayi | cyclin fold protein 1 variant b | 0.0144 | 0.0125 | 0.0106 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0936 | 0.2001 | 0.3764 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0936 | 0.2001 | 0.3917 |
Brugia malayi | histone deacetylase 11 | 0.0641 | 0.1303 | 0.1286 |
Trichomonas vaginalis | cyclins, putative | 0.0393 | 0.0714 | 0.1182 |
Echinococcus granulosus | cyclin k | 0.0144 | 0.0125 | 0.0245 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trypanosoma brucei | histone deacetylase 2 | 0.0641 | 0.1303 | 0.2363 |
Echinococcus multilocularis | cyclin k | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Schistosoma mansoni | histone deacetylase | 0.2248 | 0.5109 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2248 | 0.5109 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0846 | 0.1788 | 0.3337 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0936 | 0.2001 | 0.3764 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0936 | 0.2001 | 0.3917 |
Echinococcus granulosus | histone deacetylase 3 | 0.2248 | 0.5109 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0936 | 0.2001 | 0.3764 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.