Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cyclin b3 | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Entamoeba histolytica | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Schistosoma mansoni | cyclin B3 | 0.1265 | 0.2781 | 0.5444 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.1265 | 0.2781 | 0.2767 |
Plasmodium vivax | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Plasmodium falciparum | protein kinase 5 | 0.0936 | 0.2001 | 0.3764 |
Schistosoma mansoni | cyclin l | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0936 | 0.2001 | 0.3917 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0846 | 0.1788 | 0.1772 |
Giardia lamblia | Kinase, CMGC CDK | 0.0936 | 0.2001 | 0.3764 |
Entamoeba histolytica | cyclin, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | cyclins, putative | 0.0846 | 0.1788 | 0.3337 |
Brugia malayi | Histone deacetylase family protein | 0.0641 | 0.1303 | 0.1286 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0936 | 0.2001 | 0.3917 |
Entamoeba histolytica | cyclin family protein | 0.0598 | 0.1199 | 0.2155 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0936 | 0.2001 | 0.2001 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0641 | 0.1303 | 0.1303 |
Leishmania major | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Onchocerca volvulus | 0.0846 | 0.1788 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | cyclin C | 0.0144 | 0.0125 | 0.0125 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0936 | 0.2001 | 0.3764 |
Echinococcus granulosus | histone deacetylase 7 | 0.0641 | 0.1303 | 0.255 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.2248 | 0.5109 | 1 |
Plasmodium falciparum | cyclin | 0.0598 | 0.1199 | 0.2155 |
Echinococcus multilocularis | histone deacetylase 1 | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | cyclin t1 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Leishmania major | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Brugia malayi | cell division control protein 2 homolog | 0.0936 | 0.2001 | 0.1986 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Echinococcus granulosus | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Echinococcus multilocularis | cyclin B | 0.0846 | 0.1788 | 0.35 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0641 | 0.1303 | 0.1303 |
Loa Loa (eye worm) | hypothetical protein | 0.0846 | 0.1788 | 0.1788 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0641 | 0.1303 | 0.255 |
Brugia malayi | Histone deacetylase 1 | 0.2248 | 0.5109 | 0.51 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0641 | 0.1303 | 0.255 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0641 | 0.1303 | 0.255 |
Trichomonas vaginalis | cyclin B, putative | 0.0598 | 0.1199 | 0.2155 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Echinococcus granulosus | cyclin dependent kinase | 0.0936 | 0.2001 | 0.3917 |
Trichomonas vaginalis | cyclin B3, putative | 0.0598 | 0.1199 | 0.2155 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus multilocularis | cyclin y | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | cyclins | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | cyclin y | 0.0144 | 0.0125 | 0.0245 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.2248 | 0.5109 | 0.51 |
Echinococcus granulosus | cyclin B | 0.0846 | 0.1788 | 0.35 |
Loa Loa (eye worm) | CYL-1 protein | 0.0144 | 0.0125 | 0.0125 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Schistosoma mansoni | cyclin B | 0.0846 | 0.1788 | 0.35 |
Echinococcus multilocularis | Cyclin L1 | 0.0144 | 0.0125 | 0.0245 |
Entamoeba histolytica | cyclin family protein | 0.0598 | 0.1199 | 0.2155 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0846 | 0.1788 | 0.3337 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.0144 | 0.0125 | 0.0125 |
Schistosoma mansoni | Cyclin fold protein | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus multilocularis | histone deacetylase 3 | 0.2248 | 0.5109 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0846 | 0.1788 | 0.3337 |
Loa Loa (eye worm) | histone deacetylase | 0.0641 | 0.1303 | 0.1303 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.2248 | 0.5109 | 0.5109 |
Schistosoma mansoni | cyclin k | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0936 | 0.2001 | 0.2001 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Plasmodium vivax | protein kinase Crk2 | 0.0936 | 0.2001 | 0.3764 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0641 | 0.1303 | 0.255 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.2248 | 0.5109 | 0.51 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0125 | 0.0245 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0936 | 0.2001 | 0.3764 |
Plasmodium vivax | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0936 | 0.2001 | 0.3764 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0641 | 0.1303 | 0.255 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0641 | 0.1303 | 0.7081 |
Echinococcus granulosus | Cyclin L1 | 0.0144 | 0.0125 | 0.0245 |
Trichomonas vaginalis | cyclin D, putative | 0.0598 | 0.1199 | 0.2155 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0144 | 0.0125 | 0.0245 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0936 | 0.2001 | 0.3764 |
Giardia lamblia | Kinase, CMGC CDK | 0.0936 | 0.2001 | 0.3764 |
Trichomonas vaginalis | cyclins, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | cyclins, putative | 0.0846 | 0.1788 | 0.3337 |
Schistosoma mansoni | cyclins | 0.0598 | 0.1199 | 0.2347 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.2248 | 0.5109 | 0.5109 |
Echinococcus granulosus | histone deacetylase 8 | 0.0641 | 0.1303 | 0.255 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0641 | 0.1303 | 0.2363 |
Giardia lamblia | Histone deacetylase | 0.2248 | 0.5109 | 1 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0641 | 0.1303 | 0.2363 |
Entamoeba histolytica | cyclin, putative | 0.0598 | 0.1199 | 0.2155 |
Echinococcus granulosus | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Plasmodium vivax | histone deacetylase 1, putative | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Brugia malayi | Cyclin C | 0.0144 | 0.0125 | 0.0106 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0936 | 0.2001 | 0.2001 |
Trichomonas vaginalis | cyclin D, putative | 0.0598 | 0.1199 | 0.2155 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.1265 | 0.2781 | 0.5444 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Plasmodium falciparum | histone deacetylase 2 | 0.0641 | 0.1303 | 0.2363 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0936 | 0.2001 | 0.3917 |
Leishmania major | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Loa Loa (eye worm) | hypothetical protein | 0.2248 | 0.5109 | 0.5109 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 0.0372 | 0.0372 |
Echinococcus multilocularis | cyclin B3 1 | 0.0598 | 0.1199 | 0.2347 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0936 | 0.2001 | 0.3764 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0936 | 0.2001 | 0.3917 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0936 | 0.2001 | 0.3764 |
Echinococcus granulosus | histone deacetylase 3 | 0.2248 | 0.5109 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2248 | 0.5109 | 1 |
Schistosoma mansoni | histone deacetylase | 0.2248 | 0.5109 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0936 | 0.2001 | 0.3764 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trypanosoma brucei | histone deacetylase 2 | 0.0641 | 0.1303 | 0.2363 |
Echinococcus multilocularis | cyclin k | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0936 | 0.2001 | 0.3917 |
Brugia malayi | histone deacetylase 11 | 0.0641 | 0.1303 | 0.1286 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0936 | 0.2001 | 0.3764 |
Trichomonas vaginalis | cyclins, putative | 0.0393 | 0.0714 | 0.1182 |
Echinococcus granulosus | cyclin k | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.2248 | 0.5109 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0936 | 0.2001 | 0.3764 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Brugia malayi | cyclin fold protein 1 variant b | 0.0144 | 0.0125 | 0.0106 |
Brugia malayi | hypothetical protein | 0.0144 | 0.0125 | 0.0106 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Echinococcus multilocularis | cyclin b3 | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | cyclin | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | cyclin B3 1 | 0.0598 | 0.1199 | 0.2347 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0125 | 0.0245 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0846 | 0.1788 | 0.3337 |
Giardia lamblia | Hypothetical protein | 0.0598 | 0.1199 | 0.2155 |
Leishmania major | cyclin | 0.0846 | 0.1788 | 0.3337 |
Loa Loa (eye worm) | hypothetical protein | 0.0925 | 0.1975 | 0.1975 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0936 | 0.2001 | 0.3764 |
Trypanosoma cruzi | cyclin, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | cyclins, putative | 0.0598 | 0.1199 | 0.2155 |
Trichomonas vaginalis | cyclin B, putative | 0.0846 | 0.1788 | 0.3337 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0641 | 0.1303 | 0.2363 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0641 | 0.1303 | 0.255 |
Schistosoma mansoni | cyclin G2 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0144 | 0.0125 | 0.0245 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0936 | 0.2001 | 0.3764 |
Echinococcus granulosus | cyclin t1 | 0.0144 | 0.0125 | 0.0245 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0846 | 0.1788 | 0.1772 |
Schistosoma mansoni | cyclin d | 0.0144 | 0.0125 | 0.0245 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0944 | 0.2021 | 0.3803 |
Brugia malayi | Protein kinase domain containing protein | 0.0936 | 0.2001 | 0.1986 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0936 | 0.2001 | 0.3917 |
Plasmodium falciparum | histone deacetylase 1 | 0.2248 | 0.5109 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0936 | 0.2001 | 0.3764 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | histone deacetylase | 0.2248 | 0.5109 | 1 |
Echinococcus granulosus | cyclin y | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0125 | 0.0125 |
Trypanosoma brucei | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trichomonas vaginalis | cyclins, putative | 0.0846 | 0.1788 | 0.3337 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.0641 | 0.1303 | 0.2363 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.2248 | 0.5109 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0846 | 0.1788 | 0.1788 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0936 | 0.2001 | 0.3764 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0641 | 0.1303 | 0.255 |
Trichomonas vaginalis | cyclin B, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0598 | 0.1199 | 0.2155 |
Echinococcus granulosus | cyclin A3 4 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.1265 | 0.2781 | 0.5444 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | histone deacetylase 1 | 0.2248 | 0.5109 | 1 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Trypanosoma brucei | histone deacetylase 4 | 0.0641 | 0.1303 | 0.2363 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0936 | 0.2001 | 0.3917 |
Echinococcus multilocularis | cyclin A3 4 | 0.0144 | 0.0125 | 0.0245 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0936 | 0.2001 | 0.3917 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0641 | 0.1303 | 0.1286 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.0144 | 0.0125 | 0.0245 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0846 | 0.1788 | 0.3337 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | histone deacetylase | 0.0641 | 0.1303 | 0.255 |
Echinococcus granulosus | histone deacetylase | 0.0641 | 0.1303 | 0.255 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Giardia lamblia | Cyclin A | 0.0598 | 0.1199 | 0.2155 |
Echinococcus granulosus | cyclins | 0.0598 | 0.1199 | 0.2347 |
Plasmodium falciparum | histone deacetylase, putative | 0.0641 | 0.1303 | 0.2363 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | cyclin y | 0.0144 | 0.0125 | 0.0245 |
Trypanosoma brucei | histone deacetylase 3 | 0.0641 | 0.1303 | 0.2363 |
Echinococcus granulosus | histone deacetylase 6 | 0.0641 | 0.1303 | 0.255 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.1265 | 0.2781 | 0.2781 |
Leishmania major | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Trypanosoma cruzi | cyclin 6, putative | 0.0846 | 0.1788 | 0.3337 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0936 | 0.2001 | 0.3917 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Echinococcus multilocularis | cyclin | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0641 | 0.1303 | 0.1303 |
Toxoplasma gondii | hypothetical protein | 0.0453 | 0.0858 | 0.147 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0144 | 0.0125 | 0.0125 |
Trichomonas vaginalis | histone deacetylase, putative | 0.2248 | 0.5109 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.2248 | 0.5109 | 1 |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.0144 | 0.0125 | 0.0245 |
Trypanosoma brucei | histone deacetylase 1 | 0.2248 | 0.5109 | 1 |
Echinococcus multilocularis | cyclins | 0.0598 | 0.1199 | 0.2347 |
Schistosoma mansoni | cyclin G | 0.0144 | 0.0125 | 0.0245 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.4312 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0846 | 0.1788 | 0.3337 |
Trichomonas vaginalis | cyclin A, putative | 0.0846 | 0.1788 | 0.3337 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0144 | 0.0125 | 0.0106 |
Brugia malayi | hypothetical protein | 0.0144 | 0.0125 | 0.0106 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.