Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | transient receptor potential cation channel | 0.1689 | 0.9991 | 1 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0014 | 0 | 0.5 |
Trypanosoma brucei | inositol 1,4,5-trisphosphate receptor | 0.0014 | 0 | 0.5 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0014 | 0 | 0.5 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0014 | 0.00000010478 | 0.00000010573 |
Leishmania major | hypothetical protein, conserved | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.1675 | 0.991 | 1 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0014 | 0 | 0.5 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0015 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.00000010478 | 0.0001 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0015 | 0.0009 | 0.0009 |
Leishmania major | hypothetical protein, unknown function | 0.0014 | 0 | 0.5 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0015 | 0.0009 | 0.0009 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0014 | 0.00000010478 | 0.00000010487 |
Onchocerca volvulus | 0.0014 | 0 | 0.5 | |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0014 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.00000010478 | 0.0001 |
Echinococcus multilocularis | ankyrin repeat protein | 0.1675 | 0.991 | 0.991 |
Schistosoma mansoni | transient receptor potential channel | 0.0015 | 0.0009 | 0.0009 |
Echinococcus granulosus | ankyrin repeat protein | 0.1675 | 0.991 | 0.9919 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0009 | 1 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0014 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0014 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0014 | 0.00000010478 | 0.00000010573 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0015 | 0.0009 | 0.0009 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0014 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0014 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0014 | 0 | 0.5 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0014 | 0 | 0.5 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0014 | 0.00000010478 | 0.00000010478 |
Brugia malayi | olfactory channel protein osm-9 | 0.0015 | 0.0009 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0014 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0014 | 0 | 0.5 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0014 | 0 | 0.5 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0014 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.