Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0018 | 0.0009 | 0.0009 |
Toxoplasma gondii | hypothetical protein | 0.0016 | 0 | 0.5 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0016 | 0 | 0.5 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0016 | 0 | 0.5 |
Leishmania major | hypothetical protein, unknown function | 0.0016 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.1908 | 0.9906 | 1 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0016 | 0 | 0.5 |
Echinococcus granulosus | ankyrin repeat protein | 0.1908 | 0.9906 | 0.9915 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.00000010478 | 0.0001 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0018 | 0.0009 | 0.0009 |
Schistosoma mansoni | transient receptor potential channel | 0.0016 | 0.00000010478 | 0.00000010577 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.00000010478 | 0.0001 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0018 | 0.0009 | 0.0009 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0016 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0016 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0016 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0 | 0.5 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0016 | 0 | 0.5 |
Echinococcus multilocularis | ankyrin repeat protein | 0.1908 | 0.9906 | 0.9906 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0016 | 0.00000010478 | 0.00000010487 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0016 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0009 | 1 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0016 | 0 | 0.5 |
Trypanosoma brucei | inositol 1,4,5-trisphosphate receptor | 0.0016 | 0 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.1924 | 0.9991 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0018 | 0.0009 | 0.0009 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0016 | 0 | 0.5 |
Brugia malayi | olfactory channel protein osm-9 | 0.0018 | 0.0009 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0016 | 0.00000010478 | 0.00000010478 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0016 | 0 | 0.5 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0016 | 0 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0018 | 0.0009 | 0.0009 |
Onchocerca volvulus | 0.0016 | 0 | 0.5 | |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0016 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0016 | 0.00000010478 | 0.00000010577 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0016 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.