Detailed information for compound 1757184

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 386.526 | Formula: C20H38N2O5
  • H donors: 4 H acceptors: 5 LogP: 0.85 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1N(CCCCCCN(C2CCCCC2)C(=O)C)C[C@@H]([C@H]([C@@H]1O)O)O
  • InChi: 1S/C20H38N2O5/c1-15(24)22(16-9-5-4-6-10-16)12-8-3-2-7-11-21-13-18(25)20(27)19(26)17(21)14-23/h16-20,23,25-27H,2-14H2,1H3/t17-,18+,19-,20-/m1/s1
  • InChiKey: QXVXPTFCJRZTCI-IYWMVGAKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0853 0.0853
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0853 0.0853
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0167 1 1
Leishmania major eukaryotic initiation factor 4a, putative 0.0167 1 0.5
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.1188 0.1188
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.3904 0.3904
Loa Loa (eye worm) hypothetical protein 0.0041 0.0307 0.0307
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0431 0.0431
Echinococcus granulosus eukaryotic initiation factor 4A 0.0167 1 1
Onchocerca volvulus 0.0088 0.3904 0.3711
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.2032 0.2032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0853 0.0853
Echinococcus granulosus chromobox protein 1 0.0074 0.2805 0.2805
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.3904 0.3904
Schistosoma mansoni chromobox protein 0.0074 0.2805 0.2805
Brugia malayi chromobox protein homolog 3 0.0041 0.0307 0.0307
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0167 1 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.3904 0.3904
Leishmania major eukaryotic initiation factor 4a, putative 0.0167 1 0.5
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0167 1 1
Brugia malayi jmjC domain containing protein 0.0101 0.4911 0.4911
Brugia malayi Heterochromatin protein 1 0.0074 0.2805 0.2805
Loa Loa (eye worm) hypothetical protein 0.0053 0.1188 0.1188
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.3904 0.3904
Echinococcus granulosus chromobox protein 1 0.0074 0.2805 0.2805
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0167 1 1
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0431 0.0431
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0167 1 0.5
Schistosoma mansoni jumonji domain containing protein 0.008 0.331 0.331
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0549 0.025
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0167 1 1
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0167 1 0.5
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0167 1 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0853 0.0853
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0853 0.0853
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0549 0.025
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0167 1 0.5
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.4911 0.4911
Loa Loa (eye worm) hypothetical protein 0.0053 0.1199 0.1199
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0167 1 1
Schistosoma mansoni chromobox protein 0.0074 0.2805 0.2805
Treponema pallidum ATP-dependent RNA helicase 0.0167 1 0.5
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0549 0.025
Echinococcus multilocularis chromobox protein 1 0.0074 0.2805 0.2805
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.3904 0.3904
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0853 0.0853
Loa Loa (eye worm) hypothetical protein 0.0167 1 1
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0167 1 1
Trichomonas vaginalis chromobox protein, putative 0.0074 0.2805 0.2577
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.1188 0.1188
Plasmodium falciparum eukaryotic initiation factor 4A 0.0167 1 0.5
Plasmodium vivax RNA helicase-1, putative 0.0167 1 0.5
Echinococcus multilocularis chromobox protein 1 0.0074 0.2805 0.2805
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.1188 0.1188
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0853 0.0853
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0167 1 1
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0167 1 1
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0167 1 0.5
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.2805 0.2805
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0167 1 0.5
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.4911 0.4911
Trichomonas vaginalis chromobox protein, putative 0.0074 0.2805 0.2577
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0853 0.0853
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0853 0.0853
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0167 1 0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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