Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | casein kinase I, isoform 2 | 0.4168 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.4168 | 1 | 0.5 |
Plasmodium falciparum | casein kinase 1 | 0.4168 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.4168 | 1 | 1 |
Trypanosoma cruzi | casein kinase, putative | 0.4168 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.4168 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.4168 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase i | 0.4168 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, delta isoform, putative | 0.4168 | 1 | 1 |
Echinococcus granulosus | casein kinase I alpha | 0.4168 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.4168 | 1 | 1 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.4168 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I delta | 0.4168 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.4168 | 1 | 1 |
Echinococcus multilocularis | casein kinase I delta | 0.4168 | 1 | 0.5 |
Echinococcus granulosus | casein kinase i | 0.4168 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I delta | 0.4168 | 1 | 0.5 |
Brugia malayi | casein kinase I | 0.4168 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.4168 | 1 | 0.5 |
Onchocerca volvulus | 0.4168 | 1 | 1 | |
Giardia lamblia | Kinase, CK1 Casein kinase | 0.4168 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.4168 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.4168 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-D protein kinase | 0.4168 | 1 | 0.5 |
Plasmodium vivax | casein kinase 1, putative | 0.4168 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I delta | 0.4168 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.4168 | 1 | 0.5 |
Leishmania major | casein kinase, putative | 0.4168 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.4168 | 1 | 0.5 |
Entamoeba histolytica | casein kinase, putative | 0.4168 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.4168 | 1 | 1 |
Entamoeba histolytica | casein kinase 1, putative | 0.4168 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.4168 | 1 | 0.5 |
Schistosoma mansoni | protein kinase | 0.4168 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.4168 | 1 | 0.5 |
Toxoplasma gondii | casein kinase I | 0.4168 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 30.81 % | Inhibition of recombinant human sEH expressed in Escherichia coli assessed as inhibition of substrate PHOME hydrolysis to 6-methoxy-2-naphthaldehyde at 10 ug/ml after 5 mins by fluorescence assay | ChEMBL. | 23489630 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.