Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0273 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0273 | 0.5 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0273 | 0.5 | 0.5 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0273 | 0.5 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0273 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0273 | 0.5 | 0.5 | |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0273 | 0.5 | 0.5 |
Leishmania major | oxidoreductase-like protein | 0.0273 | 0.5 | 0.5 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0273 | 0.5 | 0.5 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0273 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.