Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | hypothetical protein | 0.0004 | 0 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0005 | 0.0012 | 0.0012 |
Leishmania major | hypothetical protein, unknown function | 0.0004 | 0 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0861 | 0.9988 | 1 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0004 | 0 | 0.5 |
Echinococcus granulosus | ankyrin repeat protein | 0.0857 | 0.9947 | 0.9959 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0004 | 0 | 0.5 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0857 | 0.9947 | 0.9947 |
Toxoplasma gondii | hypothetical protein | 0.0004 | 0 | 0.5 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0004 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0005 | 0.0012 | 0.0012 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0004 | 0 | 0.5 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0005 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0012 | 1 |
Trypanosoma brucei | inositol 1,4,5-trisphosphate receptor | 0.0004 | 0 | 0.5 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0004 | 0.00000010474 | 0.00000010474 |
Schistosoma mansoni | transient receptor potential channel | 0.0004 | 0.00000010474 | 0.0000001053 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0004 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.00000010474 | 0.0001 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0004 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0004 | 0 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0004 | 0.00000010474 | 0.00000010487 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0004 | 0 | 0.5 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0004 | 0 | 0.5 |
Schistosoma mansoni | transient receptor potential channel | 0.0004 | 0.00000010474 | 0.0000001053 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0005 | 0.0012 | 0.0012 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0004 | 0 | 0.5 |
Brugia malayi | olfactory channel protein osm-9 | 0.0005 | 0.0012 | 1 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0857 | 0.9947 | 1 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0004 | 0 | 0.5 |
Onchocerca volvulus | 0.0004 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.00000010474 | 0.0001 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0005 | 0.0012 | 0.0012 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0004 | 0 | 0.5 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0004 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.