Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 1.1008 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 1.1008 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0954 | 0.0025 | 0.0025 |
Echinococcus granulosus | nervana 2 | 0.7037 | 0.606 | 0.8984 |
Entamoeba histolytica | protein kinase 2, putative | 0.7116 | 0.6139 | 0.4697 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.7418 | 0.6439 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.3669 | 0.2719 | 0.2719 |
Trypanosoma cruzi | Protein kinase B | 0.7418 | 0.6439 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 1.0706 | 0.97 | 0.97 |
Echinococcus multilocularis | nervana 2 | 0.7037 | 0.606 | 0.8984 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 1.1008 | 1 | 0.5 |
Toxoplasma gondii | AGC kinase | 1.0706 | 0.97 | 0.5 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.7116 | 0.6139 | 0.9195 |
Loa Loa (eye worm) | hypothetical protein | 0.3669 | 0.2719 | 0.2719 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.3669 | 0.2719 | 0.2719 |
Trichomonas vaginalis | AGC family protein kinase | 1.1008 | 1 | 1 |
Giardia lamblia | Kinase, AGC PKA | 0.7116 | 0.6139 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.3669 | 0.2719 | 0.2719 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.7037 | 0.606 | 0.8984 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.7037 | 0.606 | 0.8984 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.7116 | 0.6139 | 0.9195 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.7116 | 0.6139 | 0.9195 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.7418 | 0.6439 | 1 |
Entamoeba histolytica | protein kinase, putative | 1.1008 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 1.0706 | 0.97 | 0.9589 |
Trichomonas vaginalis | AGC family protein kinase | 1.1008 | 1 | 1 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.7418 | 0.6439 | 1 |
Entamoeba histolytica | protein kinase, putative | 1.1008 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.3971 | 0.3018 | 0.0514 |
Brugia malayi | Protein kinase domain containing protein | 0.3669 | 0.2719 | 0.27 |
Trichomonas vaginalis | AGC family protein kinase | 1.1008 | 1 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.7037 | 0.606 | 0.8984 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.7418 | 0.6439 | 0.5109 |
Trichomonas vaginalis | AGC family protein kinase | 0.3669 | 0.2719 | 0.0107 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 1.1008 | 1 | 1 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.3669 | 0.2719 | 0.2719 |
Trichomonas vaginalis | AGC family protein kinase | 0.3669 | 0.2719 | 0.0107 |
Brugia malayi | protein kinase C II. | 0.3669 | 0.2719 | 0.27 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.7037 | 0.606 | 0.8984 |
Trichomonas vaginalis | AGC family protein kinase | 0.3669 | 0.2719 | 0.0107 |
Brugia malayi | Hr1 repeat family protein | 0.3669 | 0.2719 | 0.27 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.7418 | 0.6439 | 0.5109 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.7116 | 0.6139 | 0.5 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.7418 | 0.6439 | 1 |
Echinococcus granulosus | serine/threonine protein kinase | 0.7418 | 0.6439 | 1 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.3669 | 0.2719 | 0.2719 |
Brugia malayi | Protein kinase domain containing protein | 0.3669 | 0.2719 | 0.27 |
Echinococcus granulosus | nervana 2 | 0.7037 | 0.606 | 0.8984 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.3669 | 0.2719 | 0.2719 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.7116 | 0.6139 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 1.1008 | 1 | 1 |
Brugia malayi | p70 ribosomal S6 kinase beta | 1.0706 | 0.97 | 0.97 |
Echinococcus multilocularis | nervana 2 | 0.7037 | 0.606 | 0.8984 |
Trichomonas vaginalis | AGC family protein kinase | 1.1008 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.