Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.1015 | 1 | 1 |
Brugia malayi | GH02984p | 0.0259 | 0.2005 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.123 | 0.123 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0259 | 0.2005 | 0.2005 |
Schistosoma mansoni | sodium/solute symporter | 0.0259 | 0.2005 | 0.2005 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.1015 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.123 | 0.123 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.2005 | 1 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0259 | 0.2005 | 0.2005 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0259 | 0.2005 | 0.5 |
Echinococcus multilocularis | solute carrier family 5 | 0.1015 | 1 | 1 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0259 | 0.2005 | 0.2005 |
Echinococcus granulosus | geminin | 0.0186 | 0.123 | 0.123 |
Schistosoma mansoni | high-affinity choline transporter | 0.0259 | 0.2005 | 0.2005 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.1015 | 1 | 1 |
Brugia malayi | Sodium:solute symporter family protein | 0.0259 | 0.2005 | 1 |
Schistosoma mansoni | inositol transporter | 0.1015 | 1 | 1 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0259 | 0.2005 | 0.2005 |
Echinococcus multilocularis | geminin | 0.0186 | 0.123 | 0.123 |
Echinococcus granulosus | solute carrier family 5 | 0.1015 | 1 | 1 |
Onchocerca volvulus | 0.0259 | 0.2005 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.2005 | 1 |
Schistosoma mansoni | inositol transporter | 0.1015 | 1 | 1 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.1015 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.