Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | Casein kinase II | 0.1066 | 0.3997 | 1 |
Trypanosoma cruzi | casein kinase II, putative | 0.1066 | 0.3997 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1066 | 0.3997 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1066 | 0.3997 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1066 | 0.3997 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1066 | 0.3997 | 0.5 |
Loa Loa (eye worm) | CMGC/CK2 protein kinase | 0.1066 | 0.3997 | 0.123 |
Echinococcus granulosus | proto oncogene serine:threonine protein kinase | 0.2509 | 1 | 1 |
Plasmodium vivax | casein kinase 2, alpha subunit, putative | 0.1066 | 0.3997 | 0.5 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.2509 | 1 | 1 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.2509 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2509 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CK2 | 0.1066 | 0.3997 | 0.5 |
Plasmodium vivax | unspecified product | 0.1066 | 0.3997 | 0.5 |
Entamoeba histolytica | casein kinase, putative | 0.1066 | 0.3997 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1066 | 0.3997 | 0.5 |
Onchocerca volvulus | Serine\/threonine protein kinase homolog | 0.2509 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1066 | 0.3997 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1066 | 0.3997 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.1066 | 0.3997 | 0.5 |
Toxoplasma gondii | CMGC kinase, CK2 family | 0.1066 | 0.3997 | 0.5 |
Leishmania major | casein kinase II, putative | 0.1066 | 0.3997 | 0.5 |
Brugia malayi | Serine/threonine-protein kinase Pim-3 | 0.2509 | 1 | 1 |
Plasmodium falciparum | casein kinase 2, alpha subunit | 0.1066 | 0.3997 | 0.5 |
Echinococcus multilocularis | proto oncogene serine:threonine protein kinase | 0.2509 | 1 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 23957453 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.